Kyoungho Suk Selected Research

Lactic Acid (Lactate)

9/2016	Metabolic reprogramming by the pyruvate dehydrogenase kinase-lactic acid axis: Linking metabolism and diverse neuropathophysiologies.
3/2016	Pyruvate Dehydrogenase Kinase-mediated Glycolytic Metabolic Shift in the Dorsal Root Ganglion Drives Painful Diabetic Neuropathy.
10/2015	Metabolic Connection of Inflammatory Pain: Pivotal Role of a Pyruvate Dehydrogenase Kinase-Pyruvate Dehydrogenase-Lactic Acid Axis.
10/2013	Pyruvate dehydrogenase kinase as a potential therapeutic target for malignant gliomas.

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Kyoungho Suk Research Topics

Disease

51	Neuroinflammatory Diseases 02/2024 - 08/2006
31	Inflammation (Inflammations) 10/2022 - 06/2003
20	Neoplasms (Cancer) 03/2024 - 02/2007
19	Neuroblastoma 05/2015 - 02/2007
17	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2022 - 10/2003
14	Brain Injuries (Brain Injury) 04/2023 - 10/2003
11	Hypothermia 01/2019 - 01/2011
9	Alzheimer Disease (Alzheimer's Disease) 02/2024 - 11/2011
9	Glioma (Gliomas) 12/2020 - 01/2002
9	Pain (Aches) 01/2018 - 08/2013
9	Hypersensitivity (Allergy) 12/2016 - 12/2005
8	Ischemia 03/2016 - 04/2002
7	Cognitive Dysfunction 02/2024 - 06/2011
7	Gliosis 02/2024 - 01/2009
7	Hypoxia (Hypoxemia) 05/2015 - 10/2002
4	Leukemia 04/2024 - 12/2011
4	Optic Neuritis (Retrobulbar Neuritis) 04/2024 - 06/2015
4	Atherosclerosis 03/2024 - 11/2006
4	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 10/2023 - 03/2013
4	Cerebellar Ataxia (Dysmetria) 02/2023 - 01/2020
4	Infections 01/2021 - 02/2008
4	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2021 - 03/2015
4	Nervous System Diseases (Neurological Disorders) 01/2020 - 04/2012
4	Parkinson Disease (Parkinson's Disease) 01/2020 - 11/2011
4	Brain Ischemia (Cerebral Ischemia) 12/2012 - 04/2002
3	Traumatic Brain Injuries (Traumatic Brain Injury) 04/2023 - 07/2012
3	Ataxia (Dyssynergia) 02/2023 - 11/2020
3	Obesity 12/2021 - 06/2015
3	Diabetic Neuropathies (Diabetic Neuropathy) 01/2021 - 01/2016
3	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2019 - 05/2013
3	Stroke (Strokes) 05/2013 - 01/2011
3	Necrosis 07/2012 - 11/2006
3	Astrocytoma (Pilocytic Astrocytoma) 03/2010 - 10/2006
3	Atherosclerotic Plaque (Atheroma) 06/2009 - 11/2006
2	Chronic Traumatic Encephalopathy 04/2023 - 01/2021
2	Muscle Cramp (Cramp) 12/2022 - 10/2022
2	Hypertension (High Blood Pressure) 12/2021 - 02/2005
2	Normal Pressure Hydrocephalus 01/2021 - 08/2014
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 03/2019
2	Infarction (Infarctions) 01/2019 - 01/2004
2	hypoglycemic encephalopathy 01/2019 - 01/2019
2	Neuralgia (Stump Neuralgia) 01/2018 - 08/2013
2	Brain Diseases (Brain Disorder) 01/2016 - 04/2010
2	Wounds and Injuries (Trauma) 02/2015 - 01/2014
2	Fibrosarcoma 07/2012 - 10/2010

Drug/Important Bio-Agent (IBA)

45	Proteins (Proteins, Gene)FDA Link 04/2024 - 04/2002
27	CytokinesIBA 12/2022 - 12/2005
22	Lipocalin-2IBA 10/2023 - 01/2009
15	Biomarkers (Surrogate Marker)IBA 02/2024 - 12/2007
14	LipopolysaccharidesIBA 04/2024 - 01/2002
13	Neuroprotective AgentsIBA 04/2021 - 10/2003
10	Messenger RNA (mRNA)IBA 04/2023 - 04/2002
9	ChemokinesIBA 05/2020 - 11/2006
9	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2016 - 10/2002
8	ProteomeIBA 07/2023 - 04/2010
7	Small Interfering RNA (siRNA)IBA 01/2023 - 12/2007
7	NF-kappa B (NF-kB)IBA 10/2010 - 12/2005
6	Phosphotransferases (Kinase)IBA 01/2023 - 03/2016
6	Peptides (Polypeptides)IBA 12/2022 - 06/2011
6	Oxidoreductases (Dehydrogenase)IBA 01/2021 - 10/2013
6	Pyruvic Acid (Pyruvate)IBA 01/2021 - 10/2013
6	Pyruvate Dehydrogenase Acetyl-Transferring KinaseIBA 11/2020 - 10/2013
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2012 - 01/2002
5	LigandsIBA 06/2019 - 11/2006
5	Oxygen (Dioxygen)IBA 03/2016 - 01/2004
4	Therapeutic UsesIBA 02/2023 - 02/2013
4	IronIBA 01/2021 - 01/2015
4	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 03/2010
4	Lactic Acid (Lactate)FDA LinkGeneric 09/2016 - 10/2013
4	EnzymesIBA 03/2016 - 11/2006
4	p38 Mitogen-Activated Protein KinasesIBA 12/2005 - 10/2002
3	Neutralizing AntibodiesIBA 04/2023 - 01/2016
3	LipidsIBA 11/2022 - 11/2006
3	Fatty Acids (Saturated Fatty Acids)IBA 05/2020 - 01/2017
3	Sodium AzideIBA 03/2019 - 03/2010
3	Acute-Phase Proteins (Acute-Phase Protein)IBA 01/2019 - 12/2013
3	Freund's AdjuvantIBA 10/2015 - 04/2014
3	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2013 - 03/2012
3	Alkylating AgentsIBA 03/2012 - 12/2009
3	Carmustine (FIVB)FDA Link 03/2012 - 12/2009
3	Immunoglobulin E (IgE)IBA 02/2011 - 12/2005
2	Amyloid (Amyloid Fibrils)IBA 02/2024 - 08/2014
2	Antimicrobial PeptidesIBA 12/2022 - 10/2022
2	CathelicidinsIBA 12/2022 - 10/2022
2	Immunoglobulin G (IgG)IBA 05/2022 - 05/2013
2	AcidsIBA 01/2021 - 11/2020
2	Matrix Metalloproteinases (MMPs)IBA 01/2021 - 10/2010
2	Chitinase-3-Like Protein 1IBA 01/2021 - 12/2011
2	ChitinasesIBA 01/2021 - 12/2011
2	InterferonsIBA 01/2020 - 12/2007
2	NeurotoxinsIBA 10/2016 - 07/2008
2	Formaldehyde (Formol)FDA Link 01/2016 - 12/2013
2	LipocalinsIBA 01/2016 - 06/2015
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 02/2013 - 01/2011
2	decursinIBA 07/2012 - 10/2010

Therapy/Procedure

8	Therapeutics 12/2023 - 12/2009
8	Induced Hypothermia 11/2013 - 05/2011
3	Drug Therapy (Chemotherapy) 01/2016 - 12/2009
2	Spinal Injections 10/2022 - 08/2013
2	Decompressive Craniectomy 01/2019 - 06/2014